SF · RB · #31
Isaac Guerendo
Not enough snaps or games yet to rate fairly.
Is Isaac Guerendo starting?
Isaac Guerendo is listed No. 4 at RB on the San Francisco 49ers depth chart. Christian McCaffrey is listed ahead of him at No. 1. Currently listed Out.
See full San Francisco 49ers depth chart ›Isaac Guerendo this week
The San Francisco 49ers play next in Week 6, at home against the Washington Commanders on Mon, Oct 19 (ESPN/ABC). Isaac Guerendo is listed No. 4 at RB going into that game.
At RB for the San Francisco 49ers, Kaelon Black and Jordan James sit ahead of him.
Isaac Guerendo wears No. 31, is 26 years old, is listed at 6' 0", 221 lbs, has 3 years of NFL experience, came out of Louisville.
Is Isaac Guerendo playing this week?
Availability not confirmed. Check back closer to game day (updated date unavailable, ESPN).
SF KR Depth
San Francisco 49ers Starting Lineup
- PK
- P
- H
- PR
- KRDeebo Samuel Sr.
Out (as of Oct 12, ESPN)
- LS
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Season Stats
| Season | Team | G | Car | Rush Yds | Rush TD | Rec | Tgt | Rec Yds | Rec TD |
|---|---|---|---|---|---|---|---|---|---|
| 2025 | SF | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2024 | SF | 16 | 84 | 420 | 4 | 15 | 16 | 152 | 0 |
| Career | 2 yrs | 23 | 84 | 420 | 4 | 15 | 16 | 152 | 0 |
Season stats from nflverse, a public NFL statistics project. Last refreshed Oct 15, 2026.
2025 vs. 2024
Career Totals
Advanced
| Season | Rushing First Downs | Rushing EPA | Receiving Air Yards | Receiving YAC | Receiving First Downs | Receiving EPA | RACR | Target Share | Air Yards Share | WOPR |
|---|---|---|---|---|---|---|---|---|---|---|
| 2025 | 0 | — | 0 | 0 | 0 | — | — | 0.0% | 0.0% | 0.00 |
| 2024 | 18 | 4.85 | 50 | 107 | 7 | 6.53 | 3.04 | 3.1% | 1.1% | 0.05 |
| Career | 18 | — | 50 | 107 | 7 | — | — | — | — | — |
Rate/share stats (target share, air yards share, WOPR, RACR/PACR, CPOE, EPA) are per-season only — never summed into a career total.
Not enough snaps or games yet to rate fairly.
2026 Game Log
No games yet.
Isaac Guerendo's 2026 game-by-game stat log.
The People's Ratings
All Depth Chart Roles
KR No. 3 (Special Teams) · RB No. 4 (Offense)
College
Louisville
See who's starting at Louisville now